Professor Ekhaguere earned a Bachelor of Science degree with Honors in Physics from the University of Ibadan. He then proceeded to the Imperial College of Science & Technology (now Imperial College of Science, Technology & Medicine) London where he earned the Diploma of Imperial College (D.I.C.) in Mathematical Physics in 1974. In 1976, he earned a Ph.D. in Mathematical Physics from the University of London (Bedford College).
Professor Ekhaguere was a Subdean, Faculty of Science, University of Ibadan(1981-82); Head, Department of Mathematics, University of Ibadan (1993-96), and Member of the University of Ibadan Governing Council (1995-97). He is a Full Professor of Mathematics (since 1988) on the faculty of the University of Ibadan.